San Francisco-based Luminai has raised $38 million in a Series B funding round, bringing total capital raised to $60 million as large health systems accelerate demand for AI-driven workflow orchestration across fragmented administrative operations. The round, announced April 9, 2026, was led by Peak XV Partners (formerly Sequoia India & Southeast Asia), with participation from new investor Define Ventures and continued backing from General Catalyst and Y Combinator. The financing will fuel Luminai's growth as large provider organizations seek scalable ways to modernize administrative work amid mounting cost pressure, staffing constraints, and increasing operational complexity.
Background
Healthcare administrative costs exceed $1 trillion annually for U.S. hospitals, representing 25-30% of total spending. Roughly 80% of healthcare data arrives unstructured via faxes, PDFs, and clinical notes-a structural constraint that has limited the effectiveness of conventional robotic process automation (RPA) and point-solution bots. With health systems looking beyond task-specific tools toward integrated AI infrastructure, Luminai's latest raise reflects broader momentum behind intelligent automation as a foundational layer in healthcare operations.
In 2022, Luminai - formerly known as DigitalBrain - secured $16 million in a Series A round, following a $3.4 million seed. The wider sector has attracted significant capital: Assort Health raised $76 million in a Series B in October 2025, while Candid Health secured $52.5 million in a Series C in February 2025 for revenue cycle management (RCM) automation.
Details
Rather than relying on brittle integrations or task-specific bots, Luminai's platform applies healthcare-trained AI to interpret unstructured inputs, generate reliable intelligence, and coordinate end-to-end processes across access, revenue cycle, compliance, and other administrative functions. The platform combines healthcare-trained AI models, a configurable workflow engine, and human-in-the-loop validation, with flexible deployment options including on-premises, customer-managed cloud, and managed infrastructure.
Customers report a 5.3x ROI within 48 days on average across seven use cases. A partnership with Cleveland Clinic-serving 15 million patients annually-validates the platform's scale. Luminai has driven over 12 million automations to date.
Shailendra Singh, Managing Partner at Peak XV Partners, highlighted the platform differentiation driving the investment. "While most vendors optimize individual tasks and point solutions, Luminai is building the intelligent orchestration layer that will define how healthcare operations function in the future," Singh said.
Founder and CEO Kesava Kirupa Dinakaran described the structural challenge the platform addresses. "Healthcare's administrative functions operate as a massive, manual coordination layer. Encoding that work into software has historically been difficult because workflows span systems and point solutions, depend on unstructured inputs, and require embedded business and clinical context at every step," Dinakaran said. "Recent advances in AI have made it possible to handle that complexity directly-not just automate isolated tasks, but execute full workflows reliably."
Quentin Clark, former CTO of Microsoft, SAP, and Dropbox, joins the board as part of the round-a signal of the governance and enterprise-scale architecture considerations that regulated deployments demand. This article builds on previously reported themes around compliance-aligned AI automation in healthcare; for deeper context on HIPAA-aligned governance frameworks in patient financial workflows, see our earlier coverage here.
Outlook
Proceeds from the Series B will fund expanded product capabilities, grow Luminai's engineering and deployment teams, and support additional enterprise customers as demand rises for reliable, scalable AI-driven automation. Product expansion aims to deepen integration with Cleveland Clinic for referral workflows, tackling thousands of daily faxes. For enterprise IT leaders evaluating AI workflow automation platforms in 2026, Luminai's raise-and the board composition it signals-underscores a market shift from isolated task automation toward end-to-end workflow orchestration purpose-built for regulated environments.
